International Conference on World Heart Care November 07-08, 2022 Paris, France

Biography:

Keyur Mavani has completed cardiovascular disease fellowship at age of 35 and working as a consultant cardiologist. He also teaches medical students, internal medicine and family medicine residents along with cardiology fellows in training. He has published some articles and presented abstracts in various conferences. He is a Clinical Assistant Professor of Medicine for about 12 years at Scranton PA and did serve in same role for Virginia Commonwealth University Richmond Virginia USA for 2 years. 

Abstract:

According to research so far, there are more than 50 % of heart failure admissions are due to heart failure with preserved ejection fraction. Given patient related factors such as lung illnesses or weight, sometimes it becomes challenging to diagnose heart failure with preserved ejection fraction. There are ways to look for diastolic heart failure (heart failure with preserved ejection fraction HEpEF, heart failure with mid range ejectgion fraction HemEF or heart failure with recovered ejection fraction HervEF) as it is important for treating patient appropriately and reduce heart failure admissions and readmissions leading to increased health care expenditure. I will be talking about how to diagnose it with various tests such as echocardiography, examination, history and sometimes invasive cardiac catheterization especially right heart catheterization.

We do not have proper and specific treatment options for diastolic CHF so far. However, there has been lot of advances made in this area of cardiology. I will discuss trials and medications approved to treat diastolic CHF along with pathophysiology related treatment options. We will shortly discuss treatment options for amyloidosis and hypertrophic cardiomyopathy as there are more advances in these area recently.

Biography:

Rajesh Kumar has completed his Ph.D. from the Department of Chemistry, Southern Methodist University and postdoctoral studies from the Department of Cardiology, Department of Pediatrics, Boston Children’s Hospital, Harvard Medical School, USA. He has been working as a Vice President of R&D in Influunt Vascular Incorporation in USA since 2021. He has published more than 8 papers in reputed journals and has been serving as the reviewer of 6 peer-reviewed journals.

 

Abstract:

Colloids, known as volume expanders, have been used as resuscitation fluids for hypovolemic shock for decades, as they create an increase plasma oncotic pressure and expand intravascular volume. However, recent studies show commonly used synthetic colloids have adverse interactions with human biological systems in vitro and in vivo. In this work, we design a low- fouling amino (N)-oxide based zwitterionic polymer as an alternative volume expander with improved biocompatibility and efficacy. We demonstrate that the polymer possesses anti-fouling ability, resisting cell interaction and deposition in major organs, and is rapidly cleared via renal filtration and hepatic circulation, reducing risks for long-term side effects. In vitro and in vivo safety studies showed absence of adverse effects on hemostasis or acute safety risks. Finally, we show that, in a head-to-head comparison with existing colloids and plasma, the zwitterionic polymer serves as more potent oncotic agents for restoring intravascular volume in a hemorrhagic shock model. Our design of N-oxide-based zwitterionic polymers may lead to the development of alternative fluid therapies to treat hypovolemic shocks and for improving fluid management in general.

 

Biography:

Dr. Melchiori Renzo is the main investigator in the Cardio-Oncology Research Group at Hospital Universitario Austral. He graduated from Universidad de Buenos Aires and completed his postdoctoral studies at Hospital Universitario Austral. Since 2020 he is investigating about the relationship between cancer and atherosclerosis.

Abstract:

Introduction: Coronary heart disease and cancer share multiple pathophysiological mechanisms. Studies have shown, many oncologic patients will develop cardiovascular events. However, there is little evidence regarding endothelial dysfunction of patients with oncologic history in primary cardiovascular prevention, and the impact it may have on the development of subclinical atheromatosis.

Purpose: This study aims to evaluate the prevalence of oncologic history in primary cardiovascular prevention, analyze the proportion of typical cardiovascular risk factors and evaluate cancer as a biological modulator of subclinical atheromatosis.

Methods: A cross-sectional study was conducted using patient records from primary cardiovascular prevention consults that included screening for subclinical atheromatosis in the carotid and ileo-femoral territory, from September 2020 to April 2022. Population characteristics were established using univariate and bivariate analysis.

Results: The study included 5209 patients, divided into Group 1 (non-oncologic patients) 5071 and Group 2 (oncologic patients) 138 (97.2 vs 2.8%). Group 2 patients were predominantly older, with a higher percentage of women and hypertension history. Adjusted linear regression analysis was performed regarding the total plaque area in relation to the oncological history. Evidence showed cancer history increases total plaque area by an average of 8 mm (95% CI of 0.2 mm to 16 mm).

Conclusion: Patients with oncologic history had a greater number and increased total area of plaques, indicating cancer is a positive modulator for the increase in total plaque area size adjusted for typical risk factors. These findings highlight the need for better cardiovascular control in oncologic patients. Further research is needed to corroborate these results and determine the underlying pathophysiological mechanisms.

Biography:

Ramachandran Muthiah, Consultant Physician & Cardiologist, Zion hospital, Azhagiamandapam, Morning Star hospital, Marthandam, Kanyakumari District, India. Born on 10/5/1966 at keezhkulam village. Mother name Swornam from this village and father Muthiah belongs to Enayam Thoppu (both parents are farmers). Completed primary school education at Anaan vilai in keezhkulam and secondary school education at Concordia Higher secondary school, Pootteti. Got married with agricultural scientist Rajula shanthy in 1992 and having one son Jeremy, separated as divorce in 2004 vindictively and thereafter further marital status prevented. Having one sister Litta padmavathy and now remaining with poor, orphan girl R.Russulsy (who sustained serious head injury due to bike hit and suffering high sugar status) as a care taker and follower.  Completed MBBS in 1988 under Madurai Kamaraj University at Tirunelveli medical college, M.D. in General Medicine in 1996, D.M. in cardiology in 2003 under Tamil Nadu Dr.MGR Medical University, Chennai, India and completed 6 months course in Interventional cardiology at Batra Hospital, New Delhi under National Board of examinations, Ministry of health, Govt of India in 2006.  Worked as medical officer in Rural health services for 5 years (keezhachekkarakudi and Aryappapuram Primary health centres, ESI hospital, Singanallur at Coimbatore) and in teaching category as Assistant Professor at Madras medical college, Coimbatore medical college, Thoothukudi medical college and Professor at Dr.SMCSI Mission hospital & Medical college, Karakonam, Trivandrum and Azeezia Medical college, Kollam. Troubled a lot in both tamil nadu and kerala states as police arrest at both kanyakumari and thoothukudi medical colleges, psychiatric custody at madural medical college, Beemapally in trivandrum and jail imprisonment in balaramapuram, trivandrum in kerala state as steps taken to finish my life and career at these states and nation. Published many papers in Cardiosource, American College of Cardiology Foundation, Case Reports in Clinical Medicine (SCIRP) and Journal of Saudi Heart Association. Special research on Rheumatic fever and Endomyocardial fibrosis in tropical belts, Myxomas, Infective endocarditis, apical hypertrophic cardiomyopathy, Ebstein’s anomaly, Rheumatic Taussig-Bing Heart, Costello syndrome and Tetralogy of Fallot.

Abstract:

Biography:

Abstract:

The topic of psycho physiological factors in the incidence of and death from cardiovascular disease has been the subject of much conjecture and a growing amount of empirical investigation. Major societal stresses that may contribute to stress cardiomyopathy mortality include those brought on by negative changes in people's economic circumstances. Therefore, a more general hypothesis of the current study suggests that it’s probable that some people would be more likely to suffer life-threatening scenarios that would undermine their psychological and physical stability in times of diminished financial security. However, pertinent investigations have shown somewhat contradictory results with a range of plausible explanations. The pattern of cardiovascular ailments in Nigeria is unquestionably impacted by the terrible position the Nigerian economy is in right now. The new cardiovascular health investigative modalities, medications, interventions, and other treatment options all come at a cost a deadly cost price: for the majority of Nigerians. Health is not cheap. At $190 per day in 011, the global bank reported that the poverty headcount ratio was: 53% (both in 2003 and 2009) (% of population) With only 4% of the country's annual budget going to the health sector, Nigeria's budgetary support for the field has remained meagre Computation in the health system has contributed immensely to the misappropriation of the meagre resources available to the health sector Research work on the prevalence of CVD in Nigeria is scanty, however, the available data have shown that there is a direct connection between the crisis and the rise of stress cardiomyopathy mortality. It is necessary, therefore, to find alternative ways to deal with stress induced diseases Intuitively, when looking al mortality among the whole population most studies of recessions prior to the financial crisis of 2007408 find that the rate of deaths is lower during recessions than during booms (for example, Ruhm, 2000). Because when people's incomes are reduced, they might cat more healthily and reduce consumption of alcohol or cigarettes (Griffith et al, 2016, Adda et al, 2009) one study also finds that recessions slow the spread of diseases transmitted by viruses, because people move less between different regions for business or leisure (Adda. 2016). Strict goals should be established for the control of risk variables at the preventative level. For the health sector to provide access to cardiac rehabilitation therapy, calculated providence should be greatly raised additionally, donations from non-profit groups and charitable foundations that, for instance, started and funded numerous open-heart operations for both adults and children across the nation should be encouraged. Finally, it is clear that economic policies and political unrest have left a pronounced surgical scar on the population’ state of health. Leaders need to understand that unfavourable policies kill more people than pandemics and armed conflicts.